Endocrine Abstracts

Cushing disease (CD) is a rare affection due to an ACTH secreting pituitary adenoma with a hypercorticism as main consequence.The aim of this study was to assess glucose tolerance anomalies in CD.Patients: Twenty-one patients with a diagnosed CD were included; The majority of them (77.3%; n=17) were female. Mean age was 34.2 (19–54 years) and mean BMI 31.9 kg/m2 (25.9–43.7). Mean progression period of ...

Low-grade gliomas are the most common brain tumor in children, accounting for 30–50% of central nervous system tumors in the pediatric age group. They can occur anywhere within the central nervous system (CNS) including the optic pathway (5%). When optic gliomas involve the hypothalamus, patients will often present endocrinopathy. Signs of such involvement can include growth failure and precocious puberty. In this report, we present the case of 8 years three months girls ...

Introduction: The 17 α-hydroxylase deficiency is a rare form of congenital adrenal hyperplasia. It is characterized by amenorrhea, impuberism, hypertension and hypokalemia. We report a case of 17α-hydroxylase deficiency in a patient with a 46,XX karyotype, which contrasted with the absence of Mullerian duct.Case report: An18-year-old female was referred for primary amenorrhea. Her parents were cousins. Her sister, who had the same features, die...